Fig. 3. Agarose gel assay for Topo II inhibition by the synthesized compounds. (A–D) Lane D, pBR322 DNA; lane T, pBR322 DNA + Topo II; lane E, pBR322 DNA + Topo II + etoposide (100 μM); other lanes, pBR322 DNA + Topo II + the synthesized compounds.
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