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| ||||
| Compound | Structure | clog P (log D) | MWt. | Nav1.3 IC50 (nM) |
| 24 |
|
3.7 (2.1) | 510.9 | 13 |
| 35 |
|
3.6 (1.3) | 524.9 | 522 |
| 36 |
|
4.65 (2.5) | 451.8 | 296 |
| 37 |
|
0.9 | 516.5 | 6675 |
| 38 |
|
2.20 (0.4) | 434.5 | 1273 |
| 39 |
|
4.40 (2.6) | 465.9 | 22 |
| 40 |
|
2.68 | 582.6 | 1955 |
| 41 |
|
3.71 (1.30) | 548.9 | 237 |
