Table 4. Analysis of sterol composition in C. albicans by GC-MS.
| Sterol | % of total sterols (C. alb.
a
) |
||||
| Control b | FLC c | 3 d | 4 d | 9 d | |
| Lanosterol | 3.9 | 19.9 | 20.3 | 22.4 | 23.1 |
| Eburicol | — | 67.2 | 63.4 | 59.0 | 54.7 |
| Obtusifoliol | — | 6.3 | 7.4 | 7.1 | 8.2 |
| Ergosterol | 90.3 | 2.5 | 4.6 | 5.8 | 9.1 |
| Unidentified | 5.8 | 4.1 | 4.3 | 5.7 | 4.9 |
aAbbreviations: C. alb. Candida albicans (ATCC SC10231).
bControl (no drug).
cTreated with FLC at 8 μg ml–1.
dTreated with compound 3, 4, 9 at 8 μg ml–1.