Table 6. In silico ADME/T prediction of the three potential compounds compared with fluconazole.

ADME/T parameters	3	4	9	Fluconazole
AlogP98	1.764	2.986	1.942	0.75
PSA	113.836	39.706	73.448	76.556
BBB penetration	—	0.14	–0.716	–1.134
Aqueous solubility	–3.964	–3.699	–3.001	–1.976
Hepatotoxicity	0.986	0.264	0.774	0.847
CYP2D6	0.673	0.356	0.326	0.217