Table 2. The EC50 and Emax values of memantine nitrates dilating aortic rings.
| Compounds | E– |
E+ |
||
| EC50 (μM) | E max (μM) | EC50 (μM) | E max (μM) | |
| MN-02 | 146.33 ± 32.80 | 42.03 ± 3.70 | — | 39.47 ± 2.41 |
| MN-03 | 94.82 ± 10.11 | 61.68 ± 1.63 | — | 51.99 ± 1.44 |
| MN-05 | 50.57 ± 4.38 | 98.19 ± 1.01 | 46.35 ± 1.56 | 101.26 ± 2.46 |
| MN-08 | 26.85 ± 7.23 | 89.76 ± 3.31 | 24.38 ± 0.97 | 94.96 ± 0.42 |
| MN-12 | 62.81 ± 8.45 | 90.50 ± 4.94 | 54.97 ± 6.87 | 96.75 ± 2.15 |
| MN-13 | 57.05 ± 1.23 | 99.37 ± 0.77 | 36.04 ± 2.02 | 101.47 ± 1.04 |
| MN-14 | 34.40 ± 10.38 | 95.36 ± 2.62 | 24.60 ± 3.37 | 97.74 ± 2.16 |
| MN-16 | 36.46 ± 6.84 | 95.79 ± 4.05 | 31.97 ± 9.55 | 100.21 ± 1.48 |