Fig. 2. Representative pIC50 curves. A. For (R)- and (S)-roemerine (3b) compared to ketanserin at the 5-HT2A receptor in the presence of 1 μM serotonin. B. For (R)- and (S)-nuciferine (3a) compared to prazosin at the α1A receptor in the presence of 0.1 μM noradrenaline. Data points are normalised and shown as the mean ± SD from triplicate readings.
