Table I.
Association between expression of TRIM58 and clinicopathological characteristics of the CRC patients.
| TRIM58 | |||
|---|---|---|---|
| Variables | Low expression n (%) | High expression n (%) | P-value |
| Sex | 0.803 | ||
| Male | 44 (54.3) | 40 (56.3) | |
| Female | 37 (45.7) | 31 (43.7) | |
| Median age (years) | 0.324 | ||
| <60 | 43 (53.1) | 32 (45.1) | |
| ≥60 | 38 (46.9) | 39 (54.9) | |
| Histological grade | 0.428 | ||
| G1 | 5 (8.2) | 5 (11.6) | |
| G2 | 55 (90.2) | 38 (88.4) | |
| G3 | 1 (1.6) | 0 (0.00) | |
| pT status | 0.004b | ||
| T1 | 2 (2.5) | 3 (4.2) | |
| T2 | 9 (11.1) | 18 (25.4) | |
| T3 | 63 (77.8) | 49 (69.0) | |
| T4 | 7 (8.6) | 1 (1.4) | |
| pN status | 0.055 | ||
| N0 | 41 (51.2) | 50 (70.4) | |
| N1 | 31 (38.8) | 17 (23.9) | |
| N2 | 8 (10%) | 4 (5.6%) | |
| pM status | 0.556 | ||
| M0 | 77 (96.3) | 69 (97.2) | |
| M1 | 3 (3.8) | 2 (2.8) | |
| Clinical stage (Duke's) | 0.025a | ||
| I | 10 (12.8) | 16 (22.5) | |
| II | 30 (38.5) | 33 (46.5) | |
| III | 38 (48.7) | 21 (29.6) | |
| IV | 0 (0.0) | 1 (1.4) | |
| Neo chemotherapy (%) | 0.17 | ||
| No | 6 (7.4) | 1(1.4) | |
| Yes | 75 (92.6) | 70 (98.6) | |
| Recurrence-metastasis | 0.025a | ||
| No | 40 (58.0) | 46 (76.7) | |
| Yes | 29 (42.0) | 14 (23.3) | |
All data are expressed as the number of patients (%). P-values were calculated using SPSS 22 using a Chi-square test. P-values <0.05 were considered to indicate statistical significance.
b
P<0.01
a
P<0.05. CRC, colorectal cancer.