Table II.

Univariate and multivariate analyses of different prognostic parameters of the CRC patients in the testing cohort (n=152).

	Univariate analysis		Multivariate analysis
Parameters	HR (95% CI)	P-value	HR (95% CI)	P-value
Sex (male vs. female)	1.1 (0.6–1.8)	0.781	1.1 (0.6–2.0)	0.689
Age (<60 vs. ≥60 years)	1.1 (0.6–1.8)	0.759	1.2 (0.7–2.1)	0.421
Neo-chemotherapy (no vs. yes)	2.4 (1.0–6.0)	0.06	1.1 (0.3–3.8)	0.831
Histological grade (G1 or G2 vs. G3 or G4)	0.4 (0.2–0.6)	<0.001	0.5 (0.9–2.2)	0.335
pT status (T1 or T2 vs. T3 or T4)	0.2 (0.05–0.5)	0.002	0.2 (0.6–0.7)	0.012
pN status (N0 vs. N1or N2)	0.3 (0.2–0.6)	<0.001	1.0 (0.2–4.7)	0.951
pM status (M0 vs. M1)	0.2 (0.09–0.6)	0.001	0.3 (0.1–0.9)	0.024
TRIM58 expression (low vs. high)	1.8 (1.0–3.0)	0.044a	1.2 (0.7–2.2)	0.562

Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using univariate or multivariate Cox proportional hazards regression in SPSS 22. P-values were calculated using univariate or multivariate Cox proportional hazards regression in SPSS 16.0. P-values <0.05 were considered to indicate statistical significance.

^aP<0.05.