Figure 2.

TMEM165 expression in HCC is correlated with aggressive clinical parameters. (A) The correlation between the levels of TMEM165 and AFP was analyzed using Pearson's correlation test. (B and C) HCC samples were classified into two subgroups based on significant clinicopathological parameters (Table II), including (B) macroscopic vascular invasion and (C) serosal invasion. Using real-time RT-PCR results from Fig. 1B, differences in TMEM165 mRNA levels between the subgroups were analyzed by a two-sample t-test. Open circle (°) and asterisk (*) are the outlier and extreme outlier samples, respectively, with 95% confidence interval and the horizontal line indicates median value. TMEM165, transmembrane protein 165; HCC, human hepatocellular carcinoma; AFP, α-fetoprotein.