Table I.
Therapeutic efficacy of TET with or without RT on CT26/tk-luc tumor growth.
| Groups | No. of mice | Tumor growth timea (days ± SE) | Tumor growth delay timeb (days ± SE) |
|---|---|---|---|
| Control | 6 | 8.0±1.8 | 0.0±0.0 |
| TET 5 mg/kg × 12 | 7 | 10.7±1.6 | 2.7±2.4 |
| TET 10 mg/kg × 6 | 7 | 10.7±1.0 | 2.7±2.1 |
| TET 20 mg/kg × 3 | 7 | 11.3±1.8 | 3.3±2.5 |
| RT (3 Gy × 6) | 7 | 18.4±2.1 | 10.4±2.8 |
| TET 10 mg/kg + RT | 7 | 23.1±1.3 | 15.1±2.2 |
a
Tumor growth time, the time required to reach eight folds of the initial tumor volume
b
tumor growth delay time, the tumor growth time of the treated group minus that of the control group. TET, tetrandrine; RT, radiotherapy.