Table 2. Inhibitory results of compound 5n and 3-AP against the normal gastric epithelial cell line GES-1 and the gastric cancer cell line MGC-803.
| Comp | IC50
a
(μM) |
|
| GES-1 | MGC-803 | |
| 5n | 27.93 ± 1.254 | 0.93 ± 0.02 |
| 3-AP | 5.40 ± 0.73 | 9.68 ± 0.93 |
aInhibitory activity was assayed by exposure for 72 h to substances and expressed as the concentration required to inhibit normal and tumor cell proliferation by 50% (IC50). Data are presented as mean ± SD of three independent experiments.