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. 2018 Apr 19;9(6):920–936. doi: 10.1039/c8md00166a

Table 1. Data taken from original paper73.

Site Location Regions Residues
1 Intracellular crevice TM3/TM4/TM5 I3.40, F3.41, L3.44, A3.45, D3.49 (TM3); I4.45, I4.48, C4.49 (TM4); Y112 (ICL1); C5.46, P5.50 (TM5)
2 G protein coupling site TM2/TM3/TM6/TM7 N39 (ICL1); T2.39, N2.40 (TM2); D3.49, R3.50 (TM3); H6.32, S6.36, F6.44 (TM6); Y7.53 (TM7); I292 (C-term)
3 The lipid interface TM5/TM6 P5.50, M5.54 (TM5); V6.41, F6.44, W6.48 (TM6)
4 C-Terminus cleft TM1/TM7 L1.45, G1.49, L1.52 (TM1); V7.47, P7.50, F7.51 (TM7)
5 Extracellular cleft TM3/TM4 C3.30, F3.31, V3.34 (TM3); L4.58, G4.57, F4.54 (TM4)