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. 2017 Sep 13;8(10):1934–1945. doi: 10.1039/c7md00248c

Table 1. Cytotoxic activity IC50* of the triphenylphosphonium betulinic and ursolic acid derivatives against the cancer cells TET21N and MCF-7.

Test compound TET21N MCF-7
6 1.26 ± 0.18 0.80 ± 0.08
7 0.98 ± 0.11 0.85 ± 0.09
8 1.28 ± 0.18 1.51 ± 0.13
9 0.74 ± 0.14 0.70 ± 0.11
10 0.95 ± 0.15 2.31 ± 0.09
14 4.4 ± 0.34 2.76 ± 0.21
15 0.81 ± 0.08 1.59 ± 0.11
16 1.18 ± 0.16 3.90 ± 0.06
BA-DCA 4.9 ± 0.2 15.89 ± 0.19
UA-DCA >10 >20
BA >25