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. 2018 Mar 16;9(5):759–782. doi: 10.1039/c7md00448f

Table 2. Clinical advantages of clozapine.

Clinical advantages of clozapine
• The only antipsychotic agent available for TRS
• Highly effective for the treatment of positive symptoms
• More effective in reducing negative symptoms than the firstly approved typical antipsychotics
• Significant improvement in the life of patients diagnosed with schizophrenia
• Improved disorganised behaviour
• Treatment with clozapine leads to reductions in the number of hospitalised patients
• Decrease in hospital costs and overall treatment expenses
• Efficacy on depression
• Shown to reduce recurrent suicidal behaviour in subjects diagnosed with the disorder
• No extrapyramidal side effects (EPSEs)
• No tardive dyskinesia
• No elevation in prolactin levels
• Chance of relapse during clozapine therapy is less than with other antipsychotics