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General home-cage daytime activity in the hours after vehicle, (A) racemic MDMA (0.3, 1.0 and 1.7 mg/kg, i.m.) or (B) R(−) MDMA (0.3, 1.0 and 1.7 mg/kg, i.m.) afternoon (16h) administrations (N = 6). Daytime activity measures are presented as normalized data (percentage of baseline). Data are expressed as mean±SEM. Dotted lines represent baseline daytime activity (100%). *p<0.05 compared with vehicle.
