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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Cancer Res. 2018 Jun 11;78(15):4126–4137. doi: 10.1158/0008-5472.CAN-17-2082

Figure 4. Gene expression targets of TET1 in vitro.

Figure 4

(A) Principal component analysis of RNA-seq data for empty vector, TET1 KO-1, KO-2 and KO-3 (in triplicate) in MDA-MB-231 cells. (B) Venn diagram overlap of genes downregulated in the TET1 KO cells. (C) Pathway analysis of genes downregulated in TET1 KO clones. X axis −log10(pvalue). (D) Venn diagram overlap of genes upregulated in the TET1 KO cells. (E) Pathway analysis of genes upregulated in TET1 KO clones.