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. 2018 Jul 10;20:169–176. doi: 10.1016/j.nicl.2018.07.008

Table 3.

Changes of hippocampal subfield volumes in patients over treatment.

Side Subfield Volume difference, mm3
Std. error F P-value
(follow-up - baseline)
L Hippocampal Tail −9.87 3.46 8.16 0.007a
L Subiculum −2.97 1.69 3.09 0.09
L CA1 −11.12 3.03 13.46 0.001a
L Hippocampal Fissure −3.97 3.27 1.48 0.23
L Presubiculum −3.80 2.31 2.70 0.11
L Parasubiculum −0.82 0.73 1.26 0.27
L Molecular Layer −10.50 2.88 13.32 0.001a
L GC-DG −6.13 2.16 8.09 0.007a
L CA3 −4.36 1.65 6.98 0.012a
L CA4 −4.67 1.88 6.14 0.018a
L Fimbria −3.82 1.59 5.75 0.022a
L HATA −0.651 0.67 0.95 0.34
R Hippocampal Tail −12.68 2.14 35.12 <0.001a
R Subiculum 0.429 2.49 0.03 0.86
R CA1 −7.64 3.29 5.39 0.03
R Hippocampal Fissure −0.68969 3.06 0.05 0.82
R Presubiculum −2.70 1.44 3.51 0.07
R Parasubiculum −0.49 0.582 0.71 0.41
R Molecular Layer −7.62 2.66 8.23 0.007a
R GC-DG −5.81 2.11 7.61 0.009a
R CA3 −3.74 1.92 3.78 0.06
R CA4 −5.27 1.96 7.25 0.011a
R Fimbria −1.37 1.00 1.88 0.18
R HATA −0.83884 0.66 1.60 0.21

Abbreviations: CA, cornu ammonis; GC-DG, granular cells layer of the dentate gyrus; L, left; R, right; HATA, hippocampus-amygdala transition area.

a

The mean difference is statistically significant after false discovery rate correction.