Table 3. Major studies for different types of LAAO devices: Lariat.
| Characteristics | Lakkireddy et al.32) | Price et al.34) | Bartus et al.33) |
|---|---|---|---|
| Study type | Prospective registry | Retrospective | Prospective |
| Population | 712 | 154 | 89 |
| Ligation success rate (%) | 98 | 94 | 96 |
| CHA2DS2-Vasc score | 3.9 | 4 | 2.8 |
| HAS-BLED | 3.4 | 3 | 2.4 |
| Anticoagulation used | 21% OAC, 80% on single antiplatelet, 20% on DAPT | 24% OAC, 24% DAPT, aspirin alone 31%, no therapy 21% | 61% on OAC at 1-year follow up |
| Annual ischemic stroke (%) | - | - | - |
| Hemorrhagic stroke (%) | - | - | 1.1 |
| Major bleeding (%) | 0 | 9.1 | - |
| Pericardial effusion/tamponade (%) | - | 10.4 | - |
| Device embolization (%) | - | - | 0 |
| Procedure related stroke (%) | 0 | 0 | 0 |
DAPT = dual antiplatelet therapy; LAAO = left atrial appendage occlusion; OAC = oral anticoagulation.