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. 2018 Aug 2;9:3040. doi: 10.1038/s41467-018-05513-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Characteristics of non-reference unique insertions. a Major transposable element in each NUI split by three different size ranges. Stacked bars represent the total number of NUI in each size range. SINE short interspersed nuclear element, LTR long terminal repeat, LINE long interspersed nuclear element, DNA DNA transposon, NONE no interspersed repeat detected. b Example of an overlapping alignment in the reference where both ends of the NUI are homologous. Yellow block, NUI; blue blocks, homologous sequences; contig, a stretch of sequence containing the NUI; ref, reference. c When two Alus recombine ectopically, the resulting alignment, as shown in the reference strand, becomes a chimeric Alu. d Percentage of breakpoint along an Alu consensus sequence. The red dashed line represents the average breakpoint percentage (0.0033%)