Table 4.
Comparison of clinicopathological findings in each subgroup
| Total | Subgroup 1 (%) | Subgroup 2 (%) | Subgroup 3 (%) | Subgroup 4 (%) | p value | ||
|---|---|---|---|---|---|---|---|
| Total | 109 | 15 (13.8) | 15 (13.8) | 32 (43.0) | 47 (43.1) | ||
| Sex | Men : Women | 57 : 52 | 13 : 2 | 8 : 7 | 15 : 17 | 21 : 26 | N. S. |
| Age (year) | Range (median) | 40-93 (67.0) | 55-85 (71.5) | 46-79 (70.4) | 44-79 (64.5) | 40-78 (67.9) | N. S. |
| Site | Right | 40 (36.7) | 7 (46.7) | 10 (66.7) | 12 (37.5) | 11 (23.4) | < 0.05 |
| Left | 69 (63.3) | 8 (53.3) | 5 (33.3)** | 20 (62.5) | 36 (76.6)** | ||
| Macroscopic type | 0-I type | 37 (33.9) | 8 (53.3) | 6 (40.0) | 11 (34.3) | 12 (29.8) | N. S. |
| 0-IIa type | 24 (22.0) | 1 (6.7) | 2 (13.3) | 11 (34.3) | 10 (21.3) | ||
| 0-IIc type | 16 (14.7) | 4 (26.7) | 2 (13.3) | 3 (9.4) | 7 (14.9) | ||
| 0-IIa+IIc type | 28 (25.7) | 1 (6.7) | 4 (26.6) | 5 (15.7) | 17 (36.2) | ||
| LST type | 5 (4.6) | 1 (6.7) | 1 (6.7) | 2 (6.3) | 1 (2.1) | ||
| Histological type | WDA | 36 (33.0) | 9 (60.0) | 7 (46.7) | 11 (34.3) | 9 (19.1) | < 0.01 |
| MDA | 69 (63.3) | 5 (33.3)* | 7 (46.7) | 19 (59.4) | 38 (80.9)* | ||
| PAP | 2 (1.8) | 0 | 1 (6.7) | 1 (3.1) | 0 | ||
| POR | 2 (1.8) | 1 (6.7) | 0 | 1 (3.1) | 0 | ||
| pSM depth | pSM1 | 8 (7.3) | 1 (6.7) | 1 (6.7) | 4 (12.5) | 2 (4.3) | N. S. |
| pSM2 | 101 (92.7) | 14 (93.3) | 14 (93.3) | 28 (87.5) | 45 (95.7) | ||
| Lymphatic invasion | Low | 104 (95.4) | 14 (93.3) | 15 | 29 (90.6) | 46 | N. S. |
| High | 5 (4.6) | 1 (6.7) | 0 | 3 (9.4) | 1 | ||
| Venous invasion | Low | 102 (93.6) | 14 (93.3) | 15 | 28 (87.5) | 45 (95.7) | N. S. |
| High | 7 (6.4) | 1 (6.7) | 0 | 4 (12.5) | 2 (4.3) | ||
| pN | pN0 | 80 (73.4) | 12 (80.0) | 6 (40.0) | 24 (75.0) | 38 (80.9) | < 0.05 |
| pN1 | 29 (26.6) | 3 (20.0) | 9 (60.0)*, ** | 8 (25.0)* | 9 (19.1)** | ||
| Tumor budding | Low | 99 (90.8) | 14 (93.3) | 13 (86.7) | 29 (90.6) | 43 (91.5) | N. S. |
| High | 10 (9.2) | 1 (6.7) | 2 (13.3) | 3 (9.4) | 4 (8.5) |
*: p < 0.05, **: p < 0.01
Macroscopic type: I, protruded type; IIa, flat elevated type; IIc, flat depressed type; LST, laterally spreading tumor; WDA, well-differentiated adenocarcinoma; MDA, moderately differentiated adenocarcinoma; PAP, papillary adenocarcinoma; POR, poorly differentiated adenocarcinoma.