Table 2.
Comparison of clinic-pathological characteristics between female and male elderly thyroid cancer patients from the SEER database.
| Factors | Female N (%) |
Male N (%) |
P value |
|---|---|---|---|
| Married status | |||
| Married | 3,005 (52.7) | 1,814 (78.1) | |
| Widowed | 1,577 (27.7) | 189 (8.1) | |
| Separated or divorced | 610 (10.7) | 146 (6.3) | |
| Single or unmarried | 509 (8.9) | 173 (7.5) | <0.001 |
| Ethnicity | |||
| White | 4,746 (79.7) | 2,026 (84.0) | |
| African-American | 368 (6.2) | 101 (4.2) | |
| Other | 840 (14.1) | 284 (11.8) | <0.001 |
| Insurance status | |||
| Uninsured | 125 (2.6) | 48 (2.5) | |
| Insured | 4,640 (97.4) | 1,859 (97.5) | 0.805 |
| Histology subgroup | |||
| C-PTC | 3,314 (55.2) | 1,340 (55.0) | |
| V-PCT | 1,930 (32.1) | 673 (27.6) | |
| FCT | 454 (7.6) | 225 (9.2) | |
| MTC | 153 (2.5) | 118 (4.8) | |
| ATC | 158 (2.6) | 82 (3.4) | <0.001 |
| Grade | |||
| Well differentiated | 810 (59.6) | 311 (53.4) | |
| Moderately differentiated | 244 (18.0) | 97 (16.7) | |
| Poorly differentiated | 91 (6.7) | 60 (10.3) | |
| Undifferentiated | 214 (15.7) | 114 (19.6) | 0.004 |
| Tumor size (cm) | |||
| < 1.0 | 2,135 (38.1) | 611 (27.7) | |
| 1.1 - 2.0 | 1,466 (26.2) | 484 (21.9) | |
| 2.1 - 4.0 | 1275 (22.8) | 590 (26.7) | |
| > 4.0 | 725 (12.9) | 521 (23.6) | <0.001 |
| Surgery | |||
| No surgery | 357 (6.1) | 206 (8.7) | |
| Lobectomy | 838 (14.3) | 314 (13.2) | <0.001 |
| Total thyroidectomy | 4,677 (79.6) | 1,856 (78.1) | |
| Radiotherapy | |||
| Yes | 2,596 (43.5) | 1,245 (51.3) | |
| No | 3,372 (56.5) | 1,181 (48.7) | <0.001 |
| Lymph nodes resection | |||
| Yes | 2,339 (39.1) | 1,031 (42.5) | |
| No | 3,641 (60.9) | 1,394 (57.5) | 0.004 |
| AJCC 6th T stage | |||
| T0 | 15 (0.3) | 14 (0.6) | |
| T1/T2 | 3,904 (68.5) | 1,303 (57.1) | |
| T3/T4 | 1,783 (31.3) | 966 (42.3) | <0.001 |
| AJCC 6th N stage | |||
| No | 4,823 (85.3) | 1,610 (72.4) | |
| Yes | 831 (14.7) | 614 (27.6) | <0.001 |
| Distant metastasis | |||
| No | 5,585 (95.2) | 2,146 (90.4) | |
| Yes | 279 (4.8) | 228 (9.6) | <0.001 |
| AJCC 6th TNM stage | |||
| I | 2,850 (50.7) | 779 (34.5) | |
| II | 682 (12.1) | 282 (12.5) | |
| III | 1,086 (19.3) | 501 (22.2) | |
| IV | 999 (17.8) | 699 (30.9) | <0.001 |
Abbreviations: AJCC American Joint Committee on Cancer, TNM tumor-node-metastasis, C-PTC Classic Papillary Thyroid Cancer, VPTC Variant Papillary Thyroid Cancer, FTC, follicular thyroid c