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AHRR silencing upregulates secretion of TNF, IL-8, and IL-1β. (A) AHRR expression was inhibited by AHRR silencing, and AHR was down-regulated simultaneously (*P<0.05). (B) AHRR-silenced GES-1, AGS, and SGC7901 cells produced more TNF, IL-8, and IL-1β after coculture with H. pylori for 24 h (*P<0.05 vs. UNTR group, scrambled siRNA group, and AHRR-siRNA group; #P<0.05 vs. AHRR-siRNA group). UNTR: untreated group.
