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. 2018 Jul;10(Suppl 19):S2280–S2294. doi: 10.21037/jtd.2018.03.168

Figure 2.

Figure 2

Genomic sketch map of replication-defective HAdV-3. (A) Genomic organization and transcription map of HAdV-3 strains GZ1 (GenBank No. JQ824845.1). Arrows indicate the locations of coding regions. Early and late transcription units are shown with brackets; (B) replication-deficient HAdV-3 replicates in HEK293 cells expressing the E1B-55K protein from HAdV-3; (C) replication-deficient HAdV-3 whose E4-ORF6 gene is replaced by HAdV-5 E4-ORF6 replicates in HEK293 cells. DBP, DNA-binding protein; pTP, terminal protein precursor; MLP, major late promoter.