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(a) Uniformity of six different HepG2 spheroid samples at an initial seeding density of 15.000 cells/mL at day 6 post-seeding. (b) Metabolic activity of monolayer compared to spheroidal cultures after 4 h incubation with alamarBlue® at day 6 post-seeding (n = 3; *p < 0.05). Data points are expressed as mean values ± SD.
