Figure EV3. The knockdown of cav‐1 slightly enhances the accumulation of SKN‐1 in neurons but has no effect on truncated HSF‐1.

• A, B
  Worms that express a GFP‐tagged SKN‐1 (strain LG344) or HSF‐1 (strain AM583) were either treated from hatching with daf‐2 or cav‐1 RNAi or left untreated. The worms were visualized by a fluorescent microscope at day 1 of adulthood. While a slight, but not significant, increase in SKN‐1::GFP signal was seen in neurons, no difference in HSF‐1::GFP distribution was observed (scale bar, 30 μm).