Figure EV1. Effects of a mitochondria‐targeted antioxidant MitoQ in DENV‐induced mtDNA release.

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A–DHuman DCs were infected with mock or DENV (MOI = 5) in the absence or presence of a mitochondria‐targeted antioxidant MitoQ (0.2 μM). The intensity of MitoSOX fluorescence (A, n = 7), the percentages of MitoSOX‐positive cells (B, n = 7), the percentages of Max (C, n = 7), and the relative abundance of mtDNA (D, n = 7) were determined. Values are means of individual measurements in each sample ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001 (paired, two‐tailed Student's t‐test).