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. 2018 Aug 1;7:F1000 Faculty Rev-1170. [Version 1] doi: 10.12688/f1000research.14874.1

Figure 1. Localization of antimalarial targets in the asexual parasite.

Figure 1.

Shown are parasite organelles, including the nucleus, apicoplast (AP), endoplasmic reticulum (ER), food vacuole (FV), rhoptries (RH), exonemes, and vesicles. The intraerythrocytic parasite is located within the parasitophorous vacuole (PV), which is delineated by the PV membrane (PVM), where both SUB1 and SERA6 are found during egress 98. Rab11a likely localizes to vesicles, which it guides to target membranes. In the invading parasite, plasmepsin IX (PMIX) is found in the bulbs of RH and plasmepsin X (PMX) localizes to exonemes 72.