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Flow chart of the pooled study course. CaP: Ca5(PO4)3OH pentacalcium hydroxy-trisphosphate; 1. Study 4 was parallel-designed with three arms—for pooled analyses only, the CaP intervention arm was used; 2. Study 2 was cross-over-designed with two further supplements (see Methods section)—for pooled analyses, only the CaP intervention was used.
