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. 2018 Jul 16;19(7):2070. doi: 10.3390/ijms19072070

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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IL-6 and CRP serum levels in patients with isolated long-bone fracture and healthy controls. (a) IL-6 serum levels in healthy controls and in fracture patients at day 0, day 14 and day 42 after fracture. Ctl: n = 20; day 0 Fx: n = 26; day 14 Fx: n = 7; day 42 Fx: n = 4; (b) Subgroup analysis of IL-6 serum levels in male and female fracture patients after menopause at day 0 after fracture. Male Fx: n = 6; female Fx: n = 13. (c) Subgroup analysis of CRP serum levels in male and female fracture patients after menopause at day 0 after fracture. Male Fx: n = 6; female Fx: n = 13. *, p ≤ 0.05, **, p ≤ 0.01, ****, p ≤ 0.0001, ANOVA with Post hoc Fisher’s LSD, IL-6 = Interleukine-6, ctl = control, Fx = fracture, CRP = C-reactive protein.