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Changes in select signaling pathways in rat livers. * p < 0.05, ** p < 0.01 vs. control group. The P- showed the level of phosphorylated protein. The total signal proteins of NF-κB, CREB, Akt and STAT3, and the phosphorylated signal proteins of p-38, p-ERK1/2, CREB and STAT3 were induced by nano-copper.
