Table 1.
Differential expressed miRNAs in MCC or MCC-derived cell lines. See the text for details.
| Sample (n) | Method | miR↑ 1 | miR↓ 2 | Reference |
|---|---|---|---|---|
| MCC (3) | NGS 3 | miR-7 | [88] | |
| miR-9 | ||||
| miR-182 | ||||
| miR-183 | ||||
| miR-190b | ||||
| miR-340 | ||||
| miR-502-3p | ||||
| miR-873 | ||||
| miR-125b | ||||
| miR-374c | ||||
| miR-3170 | ||||
| MS-1 | NGS | miR-182 | [88] | |
| miR-183 | ||||
| miR-190b | ||||
| miR-340 | ||||
| MCPyV-positive (15) vs. MCPyV-negative MCC (13) | Microarray | miR-30a | [89] | |
| miR-34 | ||||
| miR-142-3p | ||||
| miR-1539 | ||||
| miR-181d | ||||
| MCC (14), MKL-1, MKL-2, MS-1 4 versus BCC, normal skin, MCC13, MCC26, UiOS 5 | NGS | miR-375 6 | [90] | |
| MCPyV-positive vs. MCPyV-negative MCC | Microarray | miR-30a-3p | [91] | |
| miR-30a-5p | ||||
| miR-34a | ||||
| miR-375 | ||||
| miR-769-5p | ||||
| miR-203 | ||||
| Primary vs. metastatic MCC | Microarray | miR-150 | [91] |
1 Higher levels compared to MCPyV-negative MCCs; 2 lower levels compared to MCPyV-negative MCCs; 3 next-generation sequencing; 4 MCPyV-positive MCC cell lines; 5 MCPyV-negative MCC cell lines; 6 this miR was elevated in MCC tumors and cell lines, independently of the virus state.