Figure 6.

(a) Schematic of therapeutic contact lenses embedded with a sandwiched polymeric implant with timolol-encapsulated ethyl cellulose nanoparticles; schematic showing the process of fabricating contact lenses by (b) fabrication of partially UV-polymerized contact lenses and then (c) implantation of a ring implant between partially polymerized contact lenses; (d) Photograph of implant-embedded contact lens on a male mold showing a clear 6 mm central aperture and a translucent ring (White arrow: inner margin of the implant, black arrow: outer margin of the implant); (e) Change in intraocular pressure (IOP) in rabbits treated with eye drop and timolol-laden implant-embedded contact lens. Reprinted with permission from [62].