Data-mining analysis of GPRC5a in PaCa. (A–C) Identification of differentially expressed genes (DEGs) in seven mRNA expression-profiling datasets. GPRC5a is 1 of the 85 DEGs. The red frame named A means the DEGs among GSE15471, GSE16516 and GSE 19281. The red frame named B means the DEGs among GSE22780, GSE41372 and GSE 32676. The red frame in Figure 1C means the DEGs among GSE28735, red frame A and red frame B. (D,E) Prognostic value of GPRC5a in PaCa patients with different datasets. High mRNA-level expression of GPRC5a was associated with worse overall survival in the GDC (Genomic Data Commons) TCGA PaCa (223 samples) (D) and the TCGA PaCa (196 samples) datasets (E). (F,G) Basic expression levels of GPRC5a in different organs. The protein-level expression of GPRC5a was relatively low in the pancreas compared with that in the other 43 organs (F), similar to the mRNA expression of GPRC5a (G).