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MiRNA expression affected by selumetinib. RT-qPCR of hsa-let7f-5p, hsa-miR-146b-5p and, hsa-miR-146b-5p in TPC1, C643, BCPAP and 8505C cells treated for 48 h with 1 and 10 µM selumetinib. MiRNA transcripts were normalized to RNU6B. Results are expressed relative to the untreated control. Data represent mean ± SEM of experiments performed in triplicates. * p < 0.05 regarded as significant.
