Table 1.

p-Values showing that selumetinib treatment was significant at all concentrations for all four cells lines even for the lowest used concentration. p < 0.05 regarded as significant.

Line	Contrast	Estimate	Lower	Upper	p
TPC1	0.1 vs. control	−0.07	−0.12	−0.01	0.02
TPC1	1.0 vs. control	−0.10	−0.16	−0.04	0.00
TPC1	10 vs. control	−0.14	−0.22	−0.07	0.00
TPC1	100 vs. control	−0.21	−0.30	−0.13	0.00
C643	0.1 vs. control	−0.12	−0.24	−0.00	0.04
C643	1.0 vs. control	−0.34	−0.48	−0.20	0.00
C643	10 vs. control	−0.66	−0.87	−0.46	0.00
C643	100 vs. control	−1.01	−1.32	−0.70	0.00
BCPAP	0.1 vs. control	−0.12	−0.22	−0.02	0.02
BCPAP	1.0 vs. control	−0.17	−0.29	−0.06	0.00
BCPAP	10 vs. control	−0.19	−0.32	−0.07	0.00
BCPAP	100 vs. control	−0.29	−0.44	−0.14	0.00
8505C	0.1 vs. control	−0.19	−0.23	−0.15	0.00
8505C	1.0 vs. control	−0.30	−0.36	−0.24	0.00
8505C	10 vs. control	−0.33	−0.40	−0.26	0.00
8505C	100 vs. control	−0.34	−0.42	−0.28	0.00