Table 3.
Effects of different gavage treatments on ileac villus height and crypt depth and colonic DAO and MPO activity.
| PBS | LPS | p Value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Olive Oil (n = 6) |
Fish Oil (n = 6) |
HMLE (n = 6) |
Olive Oil (n = 6) |
Fish Oil (n = 6) |
HMLE (n = 6) |
Gavage Treatment | LPS Challenge | Interaction | |
| Ileac villus height (µm) | 256.4 ± 15.3 b | 255.3 ± 18.5 b | 281.4 ± 19.7 a | 212.3 ± 22.8 c | 222.9 ± 11.9 c | 259.2 ± 15.0 ab | <0.001 | <0.001 | 0.40 |
| Ileac crypt depth (µm) | 76.9 ± 17.14 | 76.9 ± 11.9 | 80.8 ± 20.2 | 87.3 ± 14.4 | 85.6 ± 10.2 | 85.7 ± 16.9 | 0.94 | 0.10 | 0.89 |
| Colonic DAO activity (U/mg protein) | 0.21 ± 0.05 a | 0.21 ± 0.03 a | 0.20 ± 0.03 a | 0.08 ± 0.03 c | 0.12 ± 0.02 b | 0.13 ± 0.02 b | 0.36 | <0.001 | 0.05 |
| Colonic MPO activity (U/g tissue) | 0.58 ± 0.08 d | 0.63 ± 0.09 d | 0.57 ± 0.08 d | 1.98 ± 0.25 a | 1.52 ± 0.09 b | 1.30 ± 0.06 c | <0.001 | <0.001 | <0.001 |
Data are represented as the mean ± SD. Values with different letters in each row differ significantly according to one-way ANOVA and the Duncan post-hoc test (p < 0.05). The letter ‘a’ represents the highest value.