Pterostilbene enhances anti-tumor activity of cisplatin. OVCAR-8 (A,B) and Caov-3 (C,D) cells were treated with cisplatin and PTE either alone or in a combination at various concentrations in a fixed molar ratio. Cell viability was determined 48 h later (A,C). Data are expressed as the ratio to control treated with vehicle (DMSO). (B,D) Combination Index (CI) values. CI values in black diamond were determined by Chou-Talalay method using the Calcusyn software.Results are representative of 3 or more experiments, each with 3 or more replicates. *, p < 0.05, **, p < 0.005, ****, p < 0.0001, versus control treated with vehicle.