Table 2.
Genotypic and allelic distributions and frequencies (f) of apolipoprotein E in riverine populations of the Amazon.
Total |
Tapajós |
Tucuruí |
||||
---|---|---|---|---|---|---|
Genotypes | n | (%) | n | (%) | n | (%) |
𝜀2/𝜀2 | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) |
𝜀2/𝜀3 | 65 | (8.2) | 38 | (8.5) | 27 | (7.8) |
𝜀2/𝜀4 | 14 | (1.8) | 9 | (2.0) | 5 | (1.4) |
𝜀3/𝜀3 | 468 | (58.9) | 272 | (61.0) | 196 | (56.3) |
𝜀3/𝜀4 | 215 | (27.1) | 116 | (26.0) | 99 | (28.5) |
𝜀4/𝜀4 | 32 | (4.0) | 11 | (2.5) | 21 | (6.0) |
Total | 794 | (100.0) | 446 | (100.0) | 348 | (100.0) |
HWE, p-value | 0.602 | 0.902 | 0.463 | |||
Allele frequency | f | f (%) | f | f (%) | f | f (%) |
𝜀2 | 0.050 | 5.0 | 0.053 | 5.3 | 0.046 | 4.6 |
𝜀3 | 0.766 | 76.6 | 0.783 | 78.3 | 0.744 | 74.4 |
𝜀4 | 0.185 | 18.5 | 0.165 | 16.5 | 0.210 | 21.0 |
No difference was found between participants from Tapajós River basin and Lake of Tucuruí (Chi-square test, p > 0.05). HWE, Hardy–Weinberg equilibrium.