Figure 1.

Bone mineral density (BMD), lean body mass (LMB) and fat mass (FM) at the end of experiment. Px rats were fed a high fat diet supplemented with aronia, red ginseng, shiitake mushroom, and nattokinase powders (1) 0.5 g mixture/kg bw/day (AGM-L), (2) 1 g mixture/kg bw/day (AGM-H), (3) 1 g dextrin/kg bw/day (control), or (4) metformin (120 mg/kg body weight; positive-control) for 12 weeks. Sham rats fed the same diet of control. BMD (A) in the lumbar spine and femurs, LBM (B) of the hip and legs and FM of the abdomen and legs (C) were measured by DEXA. Each bar and error bar represents the mean ± SD (n = 10 of each group). ^a,b,c Different superscripts on the bars represent significant differences at p < 0.05.