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. 2018 Jul 13;10(7):901. doi: 10.3390/nu10070901

Figure 1.

Figure 1

Effects of PLE0 on OVX-induced bone loss in mice (n = 10). (A) Alteration of body weight, (B) relative uterus weight, (C) three-dimensional micro-CT images, (D) morphometric parameters in micro-CT analysis. The mice were randomly divided into the following four groups; sham-operated/water, OVX/water, OVX/ PLE0 low-dose treatment (100 mg/kg/day, PLE0 100), and OVX/PLE0 high-dose treatment (200 mg/kg/day, PLE0 200). BMD, Bone mineral density; BV/TV, bone volume per tissue volume; Tb. Th, trabecular thickness; Tb. N, trabecular number. All data are represented as mean ± standard error of the mean (SEM), and were analyzed with a one-way analysis of variance (ANOVA) and Dunnett’s post hoc test. *, p < 0.05 versus OVX alone; **, p < 0.01 versus OVX alone; and ***, p < 0.001 versus OVX alone. N.S., no significance.