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Effect of PLE0 on biochemical bone markers in OVX mice (n = 10). (A) Serum levels of C-terminal cross-linked telopeptides of type I collagen (CTX); (B) serum levels of Procollagen type 1 N-terminal propeptide (PINP). All data are represented as mean ± S.E.M. and were analyzed with a one-way analysis of variance (ANOVA) and Dunnett’s post hoc test. *, p < 0.05 versus OVX alone; and **, p < 0.01 versus OVX alone.
