Table 1.
Baseline participant characteristics * overall and stratified by intervention status.
| Overall | Magnesium (400 mg Daily) | Placebo | p-Value | |
|---|---|---|---|---|
| N | 59 | 29 | 30 | |
| Demographics | ||||
| Age, years | 61.5 ± 5.2 | 61.3 ± 5.3 | 61.6 ± 5.2 | 0.814 |
| Age category | 0.761 | |||
| ≥65 years | 14 (23.7) | 6 (20.7) | 8 (26.7) | |
| <65 years | 45 (76.3) | 23 (79.3) | 22 (73.3) | |
| Sex | 0.039 | |||
| Female | 43 (72.9) | 25 (86.2) | 18 (60.0) | |
| Male | 16 (27.1) | 4 (13.8) | 12 (40) | |
| Race | 0.612 | |||
| White | 56 (94.9) | 27 (93.1) | 29 (96.7) | |
| Nonwhite | 3 (5.1) | 2 (6.9) | 1 (3.3) | |
| Educational attainment | 0.279 | |||
| High school graduate or GED | 1 (1.7) | 0 (0) | 1 (3.3) | |
| Some college | 10 (16.9) | 6 (20.7) | 4 (13.3) | |
| College graduate | 26 (44.1) | 10 (34.5) | 16 (53.3) | |
| Graduate school or professional school | 22 (37.3) | 13 (44.8) | 9 (30) | |
| Physiologic characteristics | ||||
| Height, cm | 167.9 (9.2) | 167.1 (8.1) | 168.7 (10.3) | 0.491 |
| Weight, kg | 79.2 (18.2) | 78.0 (18.0) | 80.5 (18.7) | 0.603 |
| BMI, kg/m2 | 27.9 ± 4.6 | 27.7 ± 4.9 | 28.0 ± 4.5 | 0.804 |
| Serum magnesium, mEq/L | 1.72 ± 0.11 | 1.74 ± 0.12 | 1.71 ± 0.10 | 0.308 |
| Systolic blood pressure, mmHg | 119 ± 16 | 119 ± 14 | 119 ± 18 | 0.933 |
| Diastolic blood pressure, mmHg | 71 ± 9 | 72 ± 9 | 71 ± 10 | 0.627 |
| Antihypertensive medication | 14 (24) | 9 (31) | 5 (17) | 0.233 |
| Serum glucose, mg/dL | 98.9 ± 29.9 | 94.2 ± 10.6 | 103.2 ± 40.2 | 0.242 |
| Sensitivity analysis ** | 95.2 ± 11.1 | 94.2 ± 10.6 | 96.2 ± 11.6 | 0.494 |
| Glucose lowering medication | 2 (3.4) | 0 (0) | 2 (6.7) | 0.492 |
| PAC burden, episodes/h | 14.5 ± 58 | 8.5 ± 14 | 20.2 ± 80 | 0.437 |
| Median (25th, 75th percentiles) | 2.28 (1.22, 6.86) | 3.64 (1.31, 7.57) | 1.75 (1.12, 4.01) | |
| Log PAC burden, log(episodes/h) | 1.15 ± 1.42 | 1.26 ± 1.35 | 1.04 ± 1.49 | 0.566 |
| Median (25th, 75th percentiles) | 0.82 (0.20, 1.92) | 1.29 (0.27, 2.02) | 0.55 (0.11, 1.39) |
GED, general education diploma; BMI, body mass index; PAC, premature atrial contractions; and SD, standard deviation. * mean ± SD or n (%). ** Omission of one participant with a baseline glucose value of 307 mg/dL.