Figure 2.

LFDC are hyporesponsive for LPS stimulation. Immature DC that were cultured in the presence or absence of LF were stimulated with 1 µg/mL LPS for 48 h. (A) The median fluorescent intensity (MFI) of (A) CD83, (B) CD86, (C) PD-L1 and (D) HLA-DR was shown. The production of (E) IL-10 and (F) IL-12p70 was measured in the supernatant by CBA. The mean ± SEM of four independent experiments with 12 different donors was shown. Significance is indicated by *** = p < 0.001, ** = p < 0.01 and * = p < 0.05.