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. 2018 Jul 26;32:2058738418790318. doi: 10.1177/2058738418790318

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Increasing expression of PD-L1 predicts poor survival and recurrence in patients with COAD. (a) TMA analysis of the differentially expressed level of PD-L1 in pair-matched tumor tissues. (b) IHC analysis of the expression level and cellular localization of PD-L1 in COAD tissue cells (200×). (c) The cut-off value and AUC of PD-L1 were assessed in COAD samples (n = 240). (d) The patients with COAD were divided into PD-L1 high expression group and low expression group. (e) Kaplan–Meier analysis of the link of PD-L1 high or low expression with the OS in patients with COAD from TMA data. (f) Kaplan–Meier analysis of the link of PD-L1 high or low expression with the OS in patients with COAD from TCGA data. (g) Kaplan–Meier analysis of the link of PD-L1 high or low expression with the tumor recurrence in patients with COAD from TMA data. (h) Kaplan–Meier plotter analysis of the correlation of PD-L1 high or low expression with the OS of COAD patients with stage III + IV.