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The genetic alteration frequency and the methylation levels of PD-L1 in CRC patients. (A) The genetic alteration frequency of PD-L1 amplification, and mutation in different pathological subtypes of CRC patients. CRAD: colorectal adenocarcinoma RAD: rectal adenocarcinoma COAD: colon adenocarcinoma (B) The correlation of PD-L1 gene expression with its putative copy number alterations in CRC samples. (C) The correlation of PD-L1 gene expression with its methylation level in CRC samples.
