Table 2.
Correlation of miR-191-5p expression with clinicopathological parameters of COAD patients.
| Variables | Cases (n) | miR-191-5p expression | P-value | |
|---|---|---|---|---|
| Low (n = 195) | High (n = 45) | |||
| Age | ||||
| ⩽60 | 86 | 73 (84.9%) | 13 (15.1%) | 0.306 |
| >60 | 154 | 122 (79.2%) | 32 (20.8%) | |
| Gender | ||||
| Female | 112 | 85 (75.9%) | 27 (24.1%) | 0.067 |
| Male | 128 | 110 (85.9%) | 18 (14.1%) | |
| Pathologic stage | ||||
| I–II | 137 | 101 (73.7%) | 36 (26.3%) | 0.001 |
| III–IV | 103 | 94 (91.3%) | 9 (8.7%) | |
| Lymphatic invasion | ||||
| No | 167 | 130 (77.8%) | 37 (22.2%) | 0.048 |
| Yes | 73 | 65 (89.0%) | 8 (11.0%) | |
| Histological type | ||||
| CMA | 33 | 30 (90.9%) | 3 (9.1%) | 0.153 |
| CA | 207 | 165 (79.7%) | 42 (20.3%) | |
COAD: colon adenocarcinoma; CMA: colon mucinous adenocarcinoma; CA: colon adenocarcinoma.