Table 3.
Cox regression analysis of miR-191-5p as potential overall survival predictor.
| Variables | Univariate Cox
regression analysis |
Multivariate Cox
regression |
P-value | |
|---|---|---|---|---|
| RR (95% CI) | P-value | RR (95% CI) | ||
| Age (years) | ||||
| ⩽60 versus >60 | 0.807 (0.604–1.077) | 0.146 | ||
| Gender | ||||
| Male versus Female | 0.600 (0.350–1.028) | 0.060 | ||
| Pathologic stage | ||||
| I + II versus III + IV | 0.363 (0.212–0.619) | <0.001 | 0.403 (0.222–0.732) | 0.003 |
| Lymphatic invasion | ||||
| No versus Yes | 0.478 (0.281–0.814) | 0.007 | 0.765 (0.418–1.400) | 0.384 |
| Histological type | ||||
| CMA versus CA | 0.826 (0.405–1.687) | 0.600 | ||
| miR-191-5p expression | ||||
| Low versus High | 0.558 (0.350–0.890) | 0.014 | 0.571 (0.355–0.918) | 0.021 |
RR: relative risk; CI: confidence interval; CMA: colon mucinous adenocarcinoma; CA: colon adenocarcinoma.