Table S4.

Cox regression analysis of miR-191-5p as potential tumor recurrence predictor.

Variables	Univariate Cox regression analysis		Multivariate Cox regression
	RR (95% CI)	P value	RR(95% CI)	P value
Age(years)
≤60 vs. >60	0.807 (0.604 to 1.077)	0.146	NA	NA
Gender
Male vs Female	0.600 (0.350 to 1.028)	0.060	NA	NA
pathologic stage
I+ II vs III+ IV	0.363 (0.212 to 0.619)	< 0.001	0.480 (0.263 to0.876)	0.017
lymphatic invasion
No vs Yes	0.478 (0.281 to 0.814)	0.007	0.715 (0.398 to 1.284)	0.262
Histological type
CMA vs CA	0.826 (0.405 to 1.687)	0.600	NA	NA
PDL1 expression
Low vs High	1.637 (1.095 to 2.446)	0.016	1.397 (0.923 to 2.113)	0.114

RR: relative risk, CMA: Colon Mucinous Adenocarcinoma, CA: Colon Adenocarcinoma.