Table 4.
List of the most strongly upregulated or downregulated genes associated with transcription factors and inflammatory response in IPEC-cells.
| Gene ID | Gene Symbol | Gene Description | Fold Change | Regulation |
|---|---|---|---|---|
| Transcription Factors | ||||
| XM-003125031 | emx1 | empty spiracles homeobox 1 (EMX1) | 9.00 | up |
| GACC01000361 | nf1 | neurofibromin 1 (NF1), transcript variant 1 | 10.20 | up |
| AK347929 | tshz2 | teashirt zinc finger homeobox 2 (TSHZ2), transcript variant 1 | 12.21 | up |
| XM-003361490 | pknox2 | PBX/knotted 1 homeobox 2 | −8.33 | down |
| AY609724 | tcf21 | ref|Homo sapiens transcription factor 21 (TCF21), transcript variant 2 | −3.70 | down |
| Inflammatory Response | ||||
| XM-003131278 | prkcα | protein kinase C, alpha | 5.13 | up |
| - | - | - | 5.58 | up |
| AK396677 | pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 5.82 | up |
| XM-001929161 | osm | oncostatin M | 6.19 | up |
| XM-003130465 | il20 | interleukin 20 | 6.23 | up |
| AY669080 | bmp2 | bone morphogenetic protein 2 | 6.87 | up |
| AK232615 | serpina3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 9.85 | up |
| AK345252 | cxcl2 | chemokine (C-X-C motif) ligand 2 | −6.25 | down |
| XM-003129107 | cxcl2 | chemokine (C-X-C motif) ligand 2 | −6.25 | down |
| XM-003126166 | cxcl2 | chemokine (C-X-C motif) ligand 2 | −4.00 | down |
| NM-001001861 | cxcl2 | chemokine (C-X-C motif) ligand 2 | −3.45 | down |
| - | - | - | −3.45 | down |
| AY577905 | cxcl2 | chemokine (C-X-C motif) ligand 2 | −3.45 | down |
| NM_214029 | il1α | interleukin 1, alpha | −3.33 | down |