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Viability of pancreatic cancer cells (MIA PaCa-2, BxPC-3, CFPAC-1 and ASPC-1) and non-tumorigenic pancreas cells (HPDE) when treated with 0–300 µM of oleuropein, hydroxytyrosol or tyrosol. Values represent concentration required to achieve a 50% reduction in viability (IC50).
| Cell Line | Oleuropein (µM) | Hydroxytyrosol (µM) | Tyrosol (µM) | Gemcitabine (nM) |
|---|---|---|---|---|
| MIA PaCa-2 | 150.1 | 75.1 | >300 | 31.02 |
| BxPC-3 | >300 | >300 | >300 | 3.6 |
| CFPAC-1 | >300 | >300 | >300 | 2.6 |
| ASPC-1 | >300 | >300 | >300 | 12 |
| HPDE | >300 | 65.5 | >300 | 0.04 |
